Is Dimethylmethoxy Chromanyl Palmitate Safe

Dimethylmethoxy chromanyl palmitate is an innovative skin whitening cosmetic ingredient in market now. It is widely used in skincare formulations for its skin-brightening and anti-aging properties. It can make in creams, lotions, and serums in order to improving skin tone and reducing pigmentation. However, as with any active cosmetic ingredient, safety is a critical consideration for consumers and cosmetics manufacturers. XI AN CHEN LANG BIO TECH is dimethylmethoxy chromanyl palmitate supplier and manufacturer in global market with best price, and in this article we will explore its benefits, safety and so on. If you are looking for dimethylmethoxy chromanyl palmitate supplier, please contact us now.

What Is Dimethylmethoxy Chromanyl Palmitate CAS: 1105025-85-1     

Dimethylmethoxy chromanyl palmitate is a derivative of chromanyl, combined with palmitic acid, it is a fatty acid. This compound is designed to reduce hyperpigmentation by inhibiting melanin production. It offers a gentler alternative to harsher depigmenting agents like hydroquinone, which can cause irritation and have been linked to safety concerns in long-term use. In cosmetic applications, it is a completely elemental skin whitening active with significant whitening and photoprotective effects.

How Does Dimethylmethoxy Chromanyl Palmitate Work

The formation process of melanin is mediated by tyrosinase, which catalyzes the hydroxylation of tyrosine and converts it into melanin. 

According to the different stages of melanin production, there are the following three whitening mechanisms:

Inhibits tyrosinase production: Inhibiting the expression of tyrosinase gene in melanocytes, that is, inhibiting the synthesis of tyrosinase, reducing the content of tyrosinase, it can reduce the formation of melanin, such as vitamin A.

Inhibits tyrosinase activity: Tyrosinase is an important rate-limiting enzyme in the formation of melanin. It can catalyze the oxidation of tyrosine and gradually form dopa and dopaquinone. Dopaquinone undergoes further rearrangement, oxidation, and polymerization to form melanin.

The mechanism of inhibition of tyrosinase activity can be subdivided into: competitive inhibition, reduction inhibition and complex inhibition.

Inhibits the transfer of melanosomes: Melanin is synthesized by melanocytes in the epidermis of the skin and transferred to keratinocytes through synapses. The more melanin in keratinocytes, the darker the skin color. Inhibiting the transfer of melanin to keratinocytes can reduce the melanin content of keratinocytes and brighten skin tone, such as nicotinamide. Amino acid whitening agent is a powerful whitening agent. It has the dual functions of inhibiting tyrosinase activity and inhibiting the transfer of melanosomes. The whitening effect is comparable to that of kojic acid. Amino acid whitening agents are competitive inhibitors, non-reducing inhibitors, stable in structure and not easy to change color.

Is Dimethylmethoxy Chromanyl Palmitate Safe for Skin

Dimethylmethoxy chromanyl palmitate is safe in skin care products.

In vitro testing

HET-CAM (Eye Irritation Test): This product has no potential for eye irritation;

Neural fiber damage test: This product shows no signs of light damage;

Toxicity test on human epidermal keratinocytes: No cytotoxicity was shown at the tested concentrations used;

Toxicity test on 3T3 fibroblasts: No cytotoxicity was shown at the tested concentrations used;

Bacterial reverse mutation test (Ames test): There is no mutagenic ability among the 5 selected bacterial strains;

Toxicity testing on human melanogen cells: Product showed no cytotoxicity.

In vivo tests

Skin Carcinogenicity and Compatibility Test: Hypoallergenic testing (HRIPT) conducted on 100 volunteers aged 18-68 years showed that this product neither irritates nor causes skin sensitization.

Dimethylmethoxy Chromanyl Palmitate Benefits for Skin

Skin Brightening and Pigmentation Reduction

One of the basic benefits of dimethylmethoxy chromanyl palmitate is its ability to reduce hyperpigmentation and brighten the skin. This ingredient works by inhibiting the enzyme tyrosinase. By reducing melanin synthesis, it helps to lighten dark spots, age spots, freckles, and areas affected by hyperpigmentation.

Compared with other depigmenting agents such as hydroquinone, dimethylmethoxy chromanyl palmitate is gentler on the skin, making it ideal for long-term use without causing irritation or sensitivity. This is particularly beneficial for individuals who have sun-induced pigmentation issues or melasma and are seeking a safer alternative to traditional skin-lightening ingredients.

Evens Skin Tone

In addition to reducing dark spots, it helps in evening out the overall skin tone. Uneven skin tone is often a result of sun damage, aging, or hormonal changes. This ingredient works by targeting areas of uneven pigmentation and promoting a more uniform complexion.

Anti-Aging

While primarily known for its brightening effects, dimethylmethoxy chromanyl palmitate also offers anti-aging benefits. By reducing pigmentation and creating a more even skin tone, this ingredient can minimize the appearance of age-related skin imperfections, such as dark spots and discoloration, which often contribute to an aged appearance.

Moreover, the improvement in skin brightness and clarity gives the skin a more youthful, refreshed look. Over time, this ingredient helps to enhance overall skin radiance, making it a popular choice in anti-aging skincare formulations.

Conclusion

Dimethylmethoxy chromanyl palmitate is a new skin whitening molecule that has all the characteristics of a new type of whitening and freckle removal product. It is safe ingredient in cosmetics products. XI AN CHEN LANG BIO TECH is dimethylmethoxy chromanyl palmitate manufacturer and supplier, we provide high quality and best price in market. Please send inquiry to email: [email protected] if you want to buy dimethylmethoxy chromanyl palmitate powder.