With the development of modern society, more and more people pay attention to health issues. PQQ is a member of the vitamin family and a nutrient that has attracted much attention in recent years. It plays an important role in delaying aging, antioxidant, anti-inflammatory, neuroprotection, and so on. PQQ (pyrroloquinoline quinone) has attracted much attention from researchers and consumers for its role in delaying aging.
However, many people do not understand the safety and effectiveness of PQQ supplements, nor do they know how to choose a PQQ supplement that is suitable for them.
PQQ Safety and Efficacy
PQQ Safety
On March 1, 2022, the National Health Commission issued Document No. 1, announcing pyrroloquinoline quinone disodium salt (abbreviation: PQQ) as a new food raw material, and its safety and edible properties were recognized.
On February 2, 2023, the National Health Commission issued a new acceptance announcement for PQQ. PQQ is the first new food raw material to be accepted in 2023.
The PQQ production process applied for this time is microbial fermentation, which has passed the technical review. This means that the security of PQQ has been recognized again.
And PQQ has gathered the world's five most authoritative certifications.
In 2012, Health Canada (HC) approved PQQ as a natural health food;
In 2016, PQQ obtained GRAS certification from the U.S. Food and Drug Administration (FDA);
In addition, PQQ has been certified by the Japanese Ministry of Health, Labor and Welfare (MHLW) and the European Commission (ESFA).
PQQ Efficacy
As a coenzyme of oxidoreductase, PQQ participates in electron transfer in the respiratory chain and has a variety of biological functions.
This is also the reason why PQQ has attracted great attention in nutrition and pharmacology since its discovery. The two authoritative magazines "Nature" and "Science" have also reported its miraculous effects many times.
PQQ Recommended Dosage
Recommended Dosage: Most studies on PQQ supplements use doses between 10 to 20 mg per day. This range is considered safe for daily use in healthy adults. It’s essential to follow the dosage instructions provided by the supplement manufacturer or as advised by a healthcare professional.
Safety in Long-Term Use: While short-term studies show that PQQ is safe at recommended dosages, long-term safety data is somewhat limited. However, no significant adverse effects have been reported in the available research, and many users report positive outcomes with consistent use.
PQQ Pyrroloquinoline Quinone Potential Side Effects
Mild Side Effects: Some individuals may experience mild gastrointestinal discomfort, such as nausea or bloating, especially when starting PQQ supplementation. These side effects are generally rare and subside with regular use.
Interactions with Medications: PQQ is generally well-tolerated, but it’s always a good idea to consult a healthcare provider before starting any new supplement, particularly if you are taking medications or have underlying health conditions.
PQQ Main Functions
Anti-aging
PQQ can promote the production and function of mitochondria. As age increases, the number and function of mitochondria will gradually decrease, leading to the aging of the body. PQQ can promote the formation and repair of mitochondria, thereby delaying the aging process of the body.
Anti-oxidant
PQQ has super antioxidant ability to improve and repair mitochondrial function. Experiments have found that the antioxidant capacity of PQQ is 5,000 times that of vitamin C. It can remove excess free radicals ROS in cells, reduce oxidative stress damage to mitochondrial structure, and improve and repair mitochondrial function.
Protect Liver
PQQ can protect the liver against alcohol- and carbon tetrachloride-induced liver damage and TAA-induced liver fibrosis.
Neuroprotective Effect
PQQ can improve neuronal damage caused by oxygen and sugar deprivation models, reduce the changes in Nissl body content caused by D-galactose treatment. It Inhibits neuronal degeneration, weakens nerve damage caused by β-amyloid protein, and helps promote the secretion of neurotrophic factors.
In addition, PQQ can significantly improve the memory function of rats, and has obvious effects on memory retention and dementia prevention.
Protecting Nerve and Brain Health
PQQ can stimulate the generation and connection of nerve cells and promote communication between neurons, thereby protecting nerve and brain health, improving cognitive ability, memory, learning ability and thinking flexibility.
In addition, PQQ also plays a very important role in growth and development, body immunity, etc.
How to Choose the Right PQQ Supplement for You
Manufacturer credibility
Choose a reputable manufacturer. Understand the manufacturer's history and credibility, look for proof of sale and labels, and purchase products with recognized certification labels whenever possible.
Ingredient content
PQQ supplements should be of high purity and free of other additives and impurities. The purity of PQQ supplements should also be stated on the packaging. Learn what dosage to use with PQQ supplements to ensure safety and maximum benefits.
Some supplements may contain multiple dosages and should be used according to the instructions on the package. It is scientifically certified that 20-40mg per day can meet human body needs.
PQQ Production Process
Currently, there are three common PQQ production process on the market: Biological fermentation, biological enzyme catalysis, and chemical synthesis;
The fermentation method is difficult to meet the needs of mass production, and chemical synthesis contains many impurities and has side effects on the human body. The bioenzyme catalytic technology used by XI AN CHEN LANG BIO TECH PQQ manufacture is currently safe and has no side effects, and has passed strong international certifications such as FDA, GMP, and HACCP.
PQQ Raw Material
XI AN CHEN LANG BIO TECH uses natural high quality raw materials and uses biological enzyme catalysis technology to achieve high purity, high activity, and fast gastric acid resistance. With many years of production experience through advanced technology, our pyrroloquinoline quinone powder has obtained US FDA registration and GMP certification. It has no additives and side effects, and is safe and guaranteed. It usually takes 3-7 days for you to have obvious symptoms if use our raw PQQ powder material.
Who Should Avoid PQQ
Pregnant or Breastfeeding Women: The safety of PQQ during pregnancy and breastfeeding has not been extensively studied, so it’s best to avoid it unless recommended by a healthcare provider.
Individuals with Allergies or Sensitivities: As with any supplement, individuals with sensitivities to the ingredients in PQQ products should proceed cautiously.
Conclusion
For most people, taking PQQ pyrroloquinoline quinone powder supplement every day in recommended amounts is safe and can provide various health benefits. It has good effect on anti-aging, anti-oxidant, and improves memory. However, as with any supplement, it's crucial to monitor your body’s response and consult a healthcare professional, especially if you have specific health concerns or conditions. XI AN CHEN LANG BIO TECH supply high purity PQQ 98%+ powder in global market, Please feel free contact us if you want more information about PQQ. Please send inquiry to email: [email protected]