Alpha Glycerylphosphorylcholine

What is Alpha Glycerylphosphorylcholine Alpha GPC

Alpha Glycerylphosphorylcholine (Alpha-GPC or α-GPC) is a natural compound that is found in the brain and also derived from soy lecithin. It is a cholinergic compound that can be used as a dietary supplement to enhance cognitive function, memory, and physical performance.

Alpha GPC Details

Alpha Glycerylphosphorylcholine Benefits

Cognitive Enhancement

One of the primary benefits of GPC is its ability to enhance cognitive function. As a precursor to acetylcholine, it helps increase acetylcholine levels in the brain, which can lead to improved memory, focus, attention, and overall cognitive performance.

Neuroprotective Properties

GPC has shown promising neuroprotective properties. It may help protect neurons from damage, reduce inflammation, and support overall brain health. These properties make GPC a potential candidate for combating age-related cognitive decline and neurodegenerative diseases. 

Athletic Performance

In addition to cognitive benefits, Alpha glycerylphosphorylcholine has also been explored for its potential role in enhancing athletic performance. Some studies indicate that GPC may improve power output, reduce fatigue, and support muscle recovery, making it a popular supplement among athletes and fitness enthusiasts.

Mood and Mental Well-being

It may also have mood-enhancing effects and can help support mental well-being. By optimizing neurotransmitter levels and supporting overall brain health, GPC may help improve mood, reduce anxiety, and enhance overall mental wellness.

Anti-oxidation

Oxidation and inflammation are the main causes of aging and death of brain cells. L-α-glycerophosphocholine can scavenge free radicals in the body, fight oxidative stress, and can also reduce nuclear factor NF-κB, tumor necrosis factor TNF-α, and interleukins. The release of inflammatory factors such as IL-6 counteracts brain inflammation, thereby significantly reversing the decline of cognitive function and preventing the occurrence and development of neurodegenerative diseases.

Adjust Emotion

Dopamine can make people feel happy, and serotonin and gamma-aminobutyric acid can regulate the body's mood. L-α-glycerophosphocholine can promote the release of dopamine, upregulate the expression of dopamine transporters, improve dopamine neurotransmission in the brain, and increase the levels of serotonin in the striatum and prefrontal cortex.

It can also significantly promote the release of γ-aminobutyric acid in endogenous cortical tissue and relieve insomnia, thus exerting its anti-depressant, anxiety-relieving and mood-stabilizing effects.

Alpha Glycerylphosphorylcholine Applications

It can be used as medicine, dietary additive, sports nutrition supplement.

Advise Alpha Glycerylphosphorylcholine Alpha GPC Dosage

The standard dose of a-GPC depends on the health benefits you wish to obtain. Alpha GPC products typically recommend a daily intake of 200 mg to 600 mg.

To improve physical endurance and strength, the most commonly used dose in studies involving healthy athletes is 600 mg taken 90 minutes before physical activity or training.

Studies measuring the benefits of alpha GPC on improving cognitive function suggest that a higher dose of 1,200 mg per day, divided into three doses, may be effective in people with mild to moderate Alzheimer's disease.

It is recommended to start with the lowest effective dose of alpha GPC supplementation possible and build up gradually as needed.

Conclusion

Alpha glycerylphosphorylcholine (GPC) is a versatile compound that offers a range of potential health benefits, particularly in the areas of cognitive enhancement, neuroprotection, athletic performance, and mood support. As interest in brain health and performance continues to grow, GPC has gained popularity as a natural supplement for improving memory, focus, and overall cognitive function. While more research is needed to fully understand the mechanisms and long-term effects of GPC, current evidence suggests that it may be a valuable addition to a comprehensive approach to brain health and cognitive enhancement.