Fisetin powder is a type of flavonoid that is widely found in various plants, fruits and vegetables such as strawberries, apples, grapes, and persimmons. It is also present in other plants such as Japanese lacquer tree, American smoketree, and Chinese gooseberry.
In recent years, with the scientific community's in-depth research on fisetin, researchers find more potential benefits and applications of fisetin have been discovered in different fields. Notably, a renowned institution abroad, the Mayo Clinic, found in a comparative study that among 11 highly active natural compounds, including resveratrol, curcumin, and quercetin, fisetin had the strongest ability to clear senescent cells. It was able to remove more senescent cells in both cell and animal experiments without affecting healthy cells.
Why is Fisetin So Popular in Supplement
Fisetin plays a crucial role in plants, helping them combat oxidative stress and inflammation. In humans, fisetin has gained interest due to its potential health benefits, particularly as an antioxidant and anti-inflammatory agent. Fisetin powder, a concentrated form of the compound, is available as a dietary supplement, providing an efficient way to consume higher doses than one might obtain through diet alone. Many people take fisetin supplement in order to reverse aging, anti-oxidant and improve brain health, however, is it safe to take fisetin every day?
Can I Take Fisetin Every Day
Before taking any health supplement in our daily life, we must clearly know its effects and safety. Today let's learn fisetin powder benefits and side effects, and discuss whether daily consumption is advisable.
Fisetin Potential Benefits
Fisetin can scavenge free radicals and enhance glutathione
Fisetin powder can directly scavenge free radicals, enhance glutathione levels, and may help regulate the production of many proteins involved in protecting the body from oxidative stress and maintaining redox homeostasis. This is the mechanism by which glutathione achieves its antioxidant effects.
Anti-cancer
Activity experiments have shown that it has anti-lung cancer cells, anti-uterine cancer cells, anti-skin cancer cells and human colon cancer cells. Its main mechanism is to induce the organ differentiation of cancer cells into normal cells by transforming cancer cell genes.
Fisetin has unique effects on brain health, cognition, and memory
Much of the research in this area has been conducted at the renowned Salk Institute for Biological Studies in San Diego, focusing on its role as a "cognitive enhancer" and "neurotrophic factor." As previously mentioned, fisetin can cross the blood-brain barrier and exert a "pruning" effect by clearing senescent cells, allowing healthy cells to replace old, useless, or potentially harmful ones. Some people believed that fisetin's ability in this regard is twice that of quercetin.
Fisetin Antioxidant
Fisetin is a potent antioxidant that helps neutralize free radicals, protecting cells from oxidative damage. This activity supports cellular health and longevity, making it a valuable component of anti-aging strategies.
Anti-inflammatory
Fisetin inhibits inflammatory pathways, it helps to reduce chronic inflammation, which is a risk factor for various diseases. This can aid in maintaining joint health, cardiovascular function, and overall vitality.
Cardiovascular and Metabolic Health
Some studies suggest that fisetin may support heart health and metabolic function, potentially aiding in weight management and reducing the risk of cardiovascular diseases.
Fisetin Neuroprotective
Fisetin's ability to support brain health is well-documented. It helps protect neural cells from oxidative stress and inflammation, enhancing cognitive function and memory retention. This makes it an attractive option for those looking to support cognitive health as they age.
Fisetin Senolytic Activity
Fisetin is unique among flavonoids for its senolytic properties, meaning it can help clear senescent cells that contribute to aging and age-related diseases. This action may improve tissue function and promote healthy aging.
Recommended Dose of Fisetin
The optimal dosage of fisetin can vary depending on the specific health goals and individual factors such as age, weight, and overall health. Here are some optimal dosage of fisetin powder based on different health goals
|
Health Goal |
Recommended Dosage |
Frequency |
Notes |
|
General Health and Longevity |
100-200 mg per day |
Daily |
Supports reducing oxidative stress and inflammation |
|
Cognitive Health and Neuroprotection |
100-500 mg per day |
Daily |
May enhance memory and protect brain cells |
|
Senolytic Activity |
500-1,000 mg per day |
Intermittently (e.g., a few days per month) |
Aids in clearing senescent cells |
Combining Fisetin with Other Supplements
Fisetin can generally be taken with other supplements, but it is important to consider potential interactions and consult with a healthcare professional, especially if you are taking medications or other potent supplements. Here are some common combinations and considerations:
With Antioxidants
Fisetin can be combined with other antioxidants like resveratrol, curcumin, and quercetin to enhance its protective effects against oxidative stress. These combinations may offer synergistic benefits, particularly for anti-aging and cognitive support (The Nutrition Insider).
With Omega-3 Fatty Acids
Combining fisetin with omega-3 supplements (like fish oil) may support brain health and reduce inflammation. Omega-3s are known for their neuroprotective properties, and together with fisetin, they may improve cognitive function.
With Vitamins
Vitamins like Vitamin C and Vitamin E can complement fisetin's antioxidant activity. These vitamins can enhance overall cellular protection and support immune function (BioHackers Lab).
Can I Take Fisetin Every Day
Yes, it can take fisetin powder supplement every day. Taking fisetin daily is generally considered safe and can offer numerous health benefits. However, it is important to consult with a healthcare professional before beginning any new supplement regimen, especially if you are taking other medications or have underlying health conditions. It will have better effective if you take it with NMN, resveratrol, and quercetin.
Fisetin Safety and Side Effects
Fisetin is considered safe for most people when taken in appropriate doses. However, potential side effects can include digestive discomfort or allergic reactions in sensitive individuals. Always start with a lower dose to assess tolerance, and consult with a healthcare provider for personalized advice, especially if you have pre-existing health conditions or are pregnant or breastfeeding.
Conclusion
Fisetin powder is a promising supplement for those seeking to enhance their health and longevity. Its antioxidant, anti-inflammatory, and senolytic properties make it a valuable addition to a health regimen. With the right dosage and professional guidance, fisetin can be taken daily to support overall well-being. XI AN CHEN LANG BIO TECH is fisetin reputable manufacturers and suppliers, we supply high quality fisetin powder 98%. Please feel free contact us if you need more information about fisetin. Email: extract@chenlangbio.com