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What is Fisetin Powder

Fisetin powder extract from dry bark of Cotinus coggygria Scop. Cotinus coggygria is a plant with a long history of medicinal use and is rich in flavonoids-fisetin.

Cotinus Cotinus Extract Fisetin

Certificate of Fisetin Powder

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Benefits of Fisetin

Anti-tumor (fisetin plays an inhibitory role at all stages of tumor development);

Antioxidant, anti-inflammatory (one of the flavonoids with the strongest antibacterial effect);

Anti-aging, whitening and lightening effects (ability to remove aging cells);

Inhibit prostaglandins;

Neuroprotective effect (improves memory function);

Antidiabetic;

Antidepressant.

Fisetin Applications

Cosmetics and medicine direction;

Whitening and anti-freckle capsules (combination of resveratrol and quercetin);

Anti-tumor, anti-inflammatory, antioxidant, anti-depressant (combined with piperine) and other drugs.

Advise Fisetin Dosage

We can only take about 0.4mg from our daily diet, but if we want fisetin to provide benefits to our body, the recommended daily dose is around 100mg.

According to ClinicalTrials.gov, dosage in human trials hovers around 20mg per kilogram of bodyweight. For individuals who weigh between 100 and 250 pounds, the dosage range looks like this:

100lbs (~45kg) = 900mg per day

150lbs (~68kg) = 1,360mg per day

200lbs (~91kg) = 1,820mg per day

What Is The Best Way to Take Fisetin

This compound may prevent age-related disease by promoting natural cellular senescence. For best results, take 1-2 capsule per day with a healthy high fat meal, or as directed by your health care professional. This is equal to 100mg - 200mg of Fisetin.

What Food Is Highest In Fisetin

Plant source   Amount of Fisetin (μg /g)

Eating Fisetin-Rich Foods vs. Taking Fisetin Supplements

Researchers discovered that the average daily consumption of flavonoids per capita in Iwate was 0.4 mg. That is very different from what has been researched in two key areas:

First, It is quite low, to start. The dose in human trials at this time is around 20 mg per kilogram of body weight. That is almost 1,300 milligrams for a 150-pound individual, which is more than 3,000 times what people in Iwate naturally eat.

Second, and perhaps more intriguingly, a "hit and run" procedure is being used in human trials. This involves giving a high dose of fisetin for two days straight, followed by a lengthy hiatus (usually lasting 30 days).

To summarize, the most effective approach to reap the benefits of the flavonoid's medicinal properties is probably to take a fisetin supplement that provides approximately 20 mg/kg of bodyweight, along with some fat to improve absorption. Human trials and additional research are nevertheless required.

Can I Take NMN With Fisetin

Nicotinamide mononucleotide (NMN) and fisetin are both compounds that have gained attention for their potential health benefits, particularly in the context of aging and cellular health. While there isn't a significant body of research specifically examining the simultaneous use of NMN and fisetin, there's no known interaction between the two, and they target different pathways within the body.

NMN is a precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme involved in various cellular processes, including energy metabolism and DNA repair. Fisetin, on the other hand, is a flavonoid with antioxidant and anti-inflammatory properties that may support brain health, cardiovascular health, and longevity.

Given their distinct mechanisms of action, it's generally considered safe to take NMN and fisetin together. However, as with any supplements, it's essential to consider individual factors such as dosage, potential interactions with medications, and overall health status. Consulting with a healthcare professional before starting any new supplement regimen, especially if combining multiple supplements, is always advisable. They can provide personalized recommendations based on your specific health needs and circumstances.

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