Pyrroloquinoline quinone (PQQ), a compound found in many foods and sold as a dietary supplement, is generally well-tolerated.
Most people are completely unaware that PQQ (pyrroloquinoline quinone) supplements exist, let alone the countless health benefits it can provide. In addition to boosting energy levels, preliminary research suggests this compound may help prevent disease, reduce oxidative stress, and even act as a natural sleep aid.
PQQ is available in supplement form at health stores and pharmacies around the world, and PQQ can also be found in some foods you may already enjoy regularly. AS PQQ wholesale supplier, XI AN CHEN LANG BIO TECH supply high quality and high purity PQQ powder to global market.
What is PQQ and How It Work
Pyrroloquinoline quinone, also known as PQQ, is a compound naturally found in soil and certain foods that is believed to help form new mitochondria in cells.
It is also produced naturally in your body from other amino acids and is found in your tissues and body fluids.
PQQ can provide some major benefits to your energy, as mitochondria act as the cells’ batteries and are responsible for generating electricity.
In fact, you can often find PQQ and CoQ10 combined in supplements designed to increase energy levels and extend life.
Taking PQQ supplements is thought to help reduce inflammation, boost brain power, and even lower cholesterol levels, among many other powerful health benefits.
PQQ Benefits
- Relieve inflammation;
- Enhance brain function;
- Reduce oxidative stress;
- It can extend lifespan;
- Promote mitochondrial function;
- Lower cholesterol;
- Improve sleep.
Anti-inflammatory
Acute inflammation is a normal response of the immune system that helps fight off foreign invaders and reduce the risk of infection. On the other hand, chronic inflammation can have adverse health effects. In fact, inflammation is believed to be at the root of disease and can lead to chronic conditions such as cancer, heart disease, and diabetes.
PQQ has antioxidant properties that can help neutralize harmful free radicals and prevent cell damage and inflammation.
In fact, research published in the Journal of Nutritional Biochemistry showed that supplementing with PQQ significantly reduced many inflammatory markers after you just use three days.
In these studies, five men and five women drank a fruit-flavored beverage fortified with PQQ, resulting in potential changes in antioxidant capacity.
Enhance Brain Function
While many people start taking PQQ supplements to combat fatigue and boost energy levels, some studies have found that PQQ may actually have beneficial effects on brainpower as well.
A 2016 study found that PQQ increases blood flow to the brain, which may help prevent cognitive decline and dementia in older adults.
In a randomized, placebo-controlled, double-blind study in Japan, 41 healthy older adults received oral PQQ supplements or placebo for 12 weeks.
The researchers ultimately concluded: "The results suggest that PQQ may prevent declines in brain function, especially attention and working memory, in older adults."
Likewise, an animal study published in the Journal of Clinical Biochemistry and Nutrition showed that PQQ helped prevent neurodegeneration and improve memory in rats due to its ability to reduce oxidative damage to cells.
Reduce Oxidative Stress
Best PQQ supplement has powerful antioxidant properties that can help protect cells from damage caused by oxidative stress and the buildup of harmful free radicals. This could have far-reaching benefits, as research shows antioxidants play a central role in health and disease.
Multiple studies have confirmed PQQ’s ability to protect against oxidative stress. A test-tube study from Hokkaido University in Japan shows that PQQ helps prevent neuronal cell death caused by oxidative stress, which may benefit neurological diseases such as Parkinson's disease.
Another animal study found that PQQ reduced the risk of osteoporosis by inhibiting DNA damage, reducing cell death and blocking oxidative stress in mice.
PQQ Extend Lifespan
Impressively, some studies have actually found that taking PQQ supplements may have benefits for brain health, disease prevention, and energy production. In fact, promising new research suggests that PQQ may even serve as a life-extension tool, helping you live longer.
PQQ is integral to mitochondrial function and may be involved in controlling longevity and aging processes.
An animal study published in Experimental Gerontology actually found that supplementing with PQQ reduced oxidative stress and extended the lifespan of roundworms.
But keep in our mind that current research is limited to test tube and animal studies, and more research is needed to evaluate the effects of PQQ on human lifespan.
PQQ Promote Mitochondrial Function
One of the main benefits of PQQ is its effect on mitochondria, the organelles that provide energy to cells. In fact, it’s often combined with other energy-boosting compounds like CoQ10 to help enhance mitochondrial health.
It works by stimulating mitochondrial biogenesis, or the production of new mitochondrial cells. According to an animal study published in PLoS One, PQQ deficiency actually impairs mitochondrial function.
Symptoms of mitochondrial dysfunction may include reduced growth, muscle weakness, neurological problems, gastrointestinal problems, and increased risk of infection.
PQQ Lower Cholesterol
Cholesterol is a waxy substance found throughout the body and is important to health. It forms the basis of cell membranes and is used in the production of hormones, fat-soluble vitamins, and bile acids. However, too much cholesterol can start to clog blood vessels, forcing the heart to work harder to pump blood, increasing the risk of heart attack and stroke.
Some studies show that taking PQQ supplements can help control cholesterol levels, thereby reducing the risk of heart disease.
For example, a Japanese study showed that supplementation with pyrroloquinoline quinone disodium salt significantly reduced bad LDL cholesterol levels in 29 adults.
Improve Sleep
If you wake up frequently and still feel exhausted, PQQ may help you with this condition. PQQ not only has been shown to improve sleep quality, but also can help you fall asleep and stay asleep longer.
In a study published in Functional Foods in Health and Disease, taking PQQ for eight weeks improved multiple measures of sleep quality in 17 adults, including sleep duration, sleepiness upon awakening, and time to fall asleep.
What are the Side Effects of PQQ
Pyrroloquinoline quinone (PQQ) is a compound found in many foods and sold as a dietary supplement, however, like any supplement, it can cause side effects in some individuals if you do not use it according to your health doctor or overdose. Here are the potential side effects of PQQ:
Gastrointestinal Issues
Some users have reported stomach discomfort, nausea, or diarrhea after taking PQQ. This is one of the most commonly reported side effects of PQQ powder, likely due to how PQQ interacts with the digestive system.
Headaches
It can affect neurotransmitters and brain function, which may lead to headaches in certain individuals, especially if taken in higher doses than recommended.
Fatigue or Dizziness
Though PQQ is meant to boost energy, some people have experienced fatigue or dizziness after taking it. This could be due to individual differences in how the body processes the compound.
Allergic Reactions
In rare cases, individuals may experience allergic reactions, such as skin rashes, itching, or swelling. If you notice any signs of an allergic reaction, it is important to discontinue use and consult a healthcare professional.
Interaction with Medications
While not a direct side effect, PQQ may interact with certain medications, particularly those affecting mitochondrial function or energy metabolism. People on medication should consult their doctor before taking PQQ supplements to avoid potential adverse interactions.
Potential Liver Toxicity (at High Doses)
Some animal studies have shown that very high doses of PQQ may have toxic effects on the liver. However, these effects were observed in doses far exceeding those typically recommended for human consumption.
If you experience any adverse effects when taking PQQ supplements, it's advised to lower the dosage or stop using it and consult a healthcare provider. We need to follow recommended dosages, and speak to a doctor if we're unsure whether PQQ is right for us.
PQQ Supplement Benefits
- heart health;
- disease prevention;
- weight loss;
- improve energy;
- better brain power;
- natural sleep aid.
Heart Health
PQQ can help lower cholesterol levels, thereby reducing the risk of heart attack and stroke, while also optimizing heart health. Although research is limited, the aforementioned animal study published in PLoS One also found that PQQ was also able to reduce triglyceride levels.
Disease Prevention
Between its ability to fight free radicals and reduce oxidative stress, PQQ can have a powerful effect on disease prevention.
In addition to improving heart health and brain function, PQQ was shown to be effective against leukemia cells in a test-tube study in India.
Weight Loss
Because of PQQ's effect on energy levels, it can also help you lose weight quickly by providing the extra energy you need to get up and exercise.
Studies in humans are lacking, but the same animal study mentioned above from UC Davis and published in PLOS 1 also found that taking PQQ supplements increased metabolism in rats.
Increase Energy
PQQ is probably best known for its beneficial effects on energy levels. It stimulates the production of new mitochondrial cells, which are responsible for energy production.
PQQ has also been shown to improve sleep quality, which can also help increase energy levels.
Better Brain Power
In addition to helping prevent neurodegenerative diseases, PQQ may also enhance cognitive function. In the animal and human studies mentioned earlier, PQQ has been shown to increase blood flow to the brain and improve memory.
Natural Sleep Aid
Taking PQQ supplements or supplementing with PQQ-rich foods may be a simple and effective way to improve our sleep quality.
As previous research published in Functional Foods in Health and Disease shows, taking PQQ for eight weeks can increase sleep time, reduce waking sleepiness and reduce the time it takes to fall asleep.
Who Need PQQ
If you want to enhance your health, prevent chronic disease, and improve your energy levels, increasing your PQQ intake is a must.
Ideally, you can do this by simply changing your diet and adding more PQQ-rich foods (such as natto, kiwi, and parsley) into the mix. If you want to increase your PQQ intake even more, you may also consider taking a PQQ supplement.
To find the best PQQ supplement, be sure to buy from trustworthy and reputable brands and choose products that are extracted from fermenting bacteria rather than synthetically produced in a lab. XI AN CHEN LANG BIO TECH supply natural fermented pyrroloquinoline quinone powder 99%, we believe our high quality PQQ powder can make you do high quality PQQ finished supplements.
Please note that there is currently no set dose for PQQ, but some studies suggest that doses as low as 2 mg may be beneficial. However, most supplements come in doses between 20-40 mg, which is generally considered safe and effective for most people. Animal studies have shown that high doses of PQQ can cause negative side effects, with one study showing that 11.5 mg per kilogram of body weight had toxic effects on the kidneys of rats. Avoid taking extremely high doses to prevent potential adverse health consequences.
Please contact us email: extract@chenlangbio.com if you need more information about PQQ powder.