Chen Lang Bio: Ethylbisiminomethylguaiacol Manganese Chloride Manufacturer

XI AN CHEN LANG BIO TECH is ethylbisiminomethylguaiacol manganese chloride(EUK-134) manufacturer and supplier. We mainly do high purity EUK-134 99%. As a professional manufacturer of cosmetics raw powder, we guarantee the quality and quick ship time of our EUK-134 powder. Now we are global EUK-134 supplier.

What is Ethylbisiminomethylguaiacol Manganese Chloride

Ethylbisiminomethylguaiacol Manganese Chloride, also known as EUK-134. It is a synthetic antioxidant with a molecular weight of only 416.74, belonging to a small molecule compound. It acts as a powerful antioxidant and mimics the activity of superoxide dismutase (SOD) and catalase enzymes, and can directly enter the skin to play a role. It is highly regarded in the skincare industry for its ability to neutralize free radicals and protect the skin from oxidative stress.

Ethylbisiminomethylguaiacol Manganese Chloride Mechanism of Action

How does EUK-134 work in the human body? Let’s first understand the human body’s antioxidant system. Two important components of the human antioxidant system are superoxide dismutase (SOD) and catalase (CAT). The powerful combination of SOD and CAT can eliminate all kinds of reactive oxygen free radicals (ROS) produced during metabolism and maintain normal metabolism of the body.

However, since SOD and CAT are very unstable and have large molecular weight, it is difficult for them to enter the human body through the skin and cannot be added to cosmetics. Therefore, EUK-134 came into being.

EUK-134 is a highly purified ingredient that mimics the activity of superoxide dismutase (SOD) and catalase in the body. EUK-134 converts superoxide anions (o2-) into peroxide (H2O2) and then converts hydrogen peroxide into water (H2O) through the redox cycle of the Mn (II) ion at the center of the molecule, completing the task that can only be accomplished by the combination of SOD and CAT.

In addition, ethylbisiminomethylguaiacol manganese chloride is essentially a catalyst. Its amount does not decrease after participating in the reaction, and it can be recycled. Like enzymes, it has amazing regeneration ability and can work for a long time with a small amount. Unlike other antioxidants (such as VC, astaxanthin, etc.), it eliminates free radicals by consuming itself.

In the past 10 years, EUK-134 has been increasingly used in medical and anti-aging applications. A large amount of third-party literature has confirmed the excellent antioxidant capacity of EUK-134.

EUK-134 Skin Benefits

Reduce MMP2 Activity

Factors such as ultraviolet (UV) radiation, air pollution, and stress can increase the levels of matrix metalloproteinase 2 (MMP2), leading to collagen loss. EUK-134 can reduce MMP2 levels in skin cells, thereby preserving collagen.

Repair of UV-Induced DNA Mutations

The second function of EUK-134 is repairing UV-induced DNA mutations. Under UV radiation, thymine (T) in DNA molecules can form dimers, leading to mutations. Mutated DNA loses its activity, causing fibroblast dysfunction and skin sagging. EUK-134 can reduce the formation of T-T dimers, restoring DNA to its normal state and helping the skin regain elasticity.

Prevent Photoaging

The third function is the prevention of photoaging. Clinical studies have shown that ethylbisiminomethylguaiacol manganese chloride can reduce UV-induced redness and inflammation and decrease skin irritation caused by lipid peroxidation due to UV exposure.

Packaging and Transportation

We ensure that our ethylbisiminomethylguaiacol manganese chloride is packaged to preserve their phytochemical integrity and are transported in conditions that maintain their quality until they reach our clients.

Package

Usually use moisture-proof and light-proof sealed packaging, such as aluminum foil bags, plastic buckets or glass bottles, etc., to prevent moisture and photolysis.

The inner packaging is usually a double-layer plastic bag, and the outer packaging is a cardboard box or paper drum for enhanced protection.

Transportation

Direct sunlight, high temperature and humid environment should be avoided during transportation to maintain the stability of the medicine.

EUK-134 Storage

The storage environment should be dry, ventilated, and cool, and avoid mixing with flammable, explosive, and corrosive items.

How to Use Ethylbisiminomethylguaiacol Manganese Chloride

Ethylbisiminomethylguaiacol manganese chloride is a powerful synthetic antioxidant, also known as EUK-134. It is widely used in cosmetics and skin care products.

EUK-134 is commonly used in the following types of cosmetics

Creams and Lotions: Use in day creams, night creams, serums, and more to enhance antioxidant effects.

Sunscreen products: Combined with other sunscreen ingredients to provide additional free radical protection.

Anti-Aging Products: EUK-134 helps reduce the appearance of fine lines and wrinkles.

EUK-134 CAS 81065-76-1 Dosage

In cosmetic formulations, ethylbisiminomethylguaiacol manganese chloride is typically added at 0.01% to 0.1%. The specific additive dosage depends on the product's formulation needs and target efficacy.

0.01% - 0.05%: Suitable for products with mild antioxidant effects, such as daily moisturizers and basic skin care products.

0.05% - 0.1%: Suitable for products that require enhanced antioxidant and anti-aging effects, such as serums and anti-aging creams.

Where to Buy EUK-134 CAS 81065-76-1

XI AN CHEN LANG is antioxidant EUK 134 ethylbisiminomethylguaiacol manganese chloride manufacturer and supplier in global market. We mainly supply high quality cosmetics powder, APIs, plant extract powder. Please contact us email: extract@chenlangbio.com for EUK 134 price, benefits, side effects and so on.