Clindamycin Pharmaceutical Intermediates Powder manufacturer and Supplier

Clindamycin powder is a powerful antibiotic, it is used to treat a variety of bacterial infections. Due to its effectiveness against anaerobic bacteria, clindamycin is widely used in medicine and cosmetics. Especially in skin care products, it is very popular due to its efficacy in treating acne.

What is Clindamycin

Clindamycin is derived from lincomycin, it is a lincosamide antibiotic that inhibits bacterial protein synthesis, thereby elimination bacteria. It is available in various forms, including oral capsules, topical solutions, and injections. In the skincare industry, clindamycin is mainly used in topical formulations.

Clindamycin Basic Information

Why Choose Us for Clindamycin

Annual Production Capacity: 5000 Tons

Our factory covers an area of approximately 26,666 square meters and produces approximately 5,000 tons of plant extract powder, pharmaceutical intermediates powder products annually. So you don't have to worry about supply issues, we will send package out as soon as possible after you place an order.

Rich Experience to Manufacturer Pharmaceutical Grade Powder

Our company has 30 R&D personnel, mainly engaged in the research and development, production and sales of pharmaceutical intermediates, APIS, pharmaceutical preparations, major health products, synthetic biology products. We provide CMO/CDMO services for pharmaceutical intermediates and APIs. We are a world-renowned production and research base of cephalosporin side chain intermediates such as clarithromycin, azithromycin, cefuroxime sodium, cefprozil and biological fermentation raw material glutathione and L-Carnosine powder.

We are also a well-known domestic manufacturer of anti-infection and gynecological preparations, with a relatively rich series of cephalosporin antibiotics and gynecological full life cycle products in China.

Industry Certificates

XI AN CHEN LANG BIO TECH has passed national laboratory accreditation, quality management system ISO22000 certification, HACCP certification, HALAL certification, KOSHER certification and BRC certification.

Excellent Customer Service

Quick Response: We promise to respond quickly to customer inquiries and needs, and provide professional consultation and services.

Please directly send inquiry to email: extract@chenlangbio.com if you want to buy clindamycin powder or other pharmaceutical intermediates powder.

Mechanism of Action of Clindamycin

Inhibition of Protein Synthesis

Clindamycin binds to the 50S subunit of bacterial ribosomes and interferes with the translocation step in protein synthesis. By preventing the ribosome from moving along the mRNA, clindamycin effectively prevents the production of essential proteins that the bacteria need to grow and replicate. This bacteriostatic action means that Clindamycin stops bacteria from multiplying, allowing the body's immune system to eliminate the remaining bacteria.

Effect on Bacterial Cell Membrane

In addition to inhibiting protein synthesis, clindamycin can also alter the permeability of bacterial cell membranes. This secondary action further disrupts the integrity of the bacterial cell, leading to the leakage of essential intracellular components and ultimately to the death of the bacterial cell.

Clindamycin is Particularly Effective against the Following Bacteria

Anaerobic bacteria: These bacteria thrive in an oxygen-free environment and are usually found in deep tissues and abscesses. Clindamycin's effectiveness against anaerobic bacteria makes it the drug of choice for treating infections in areas with poor oxygen supply.

Gram-positive bacteria: These include streptococcus, staphylococcus (including methicillin-resistant Staphylococcus aureus, MRSA), and pneumococcus.

Certain protozoa: Clindamycin is also used in combination therapy to treat protozoan infections such as malaria, especially when other treatments are not effective.

What is Clindamycin Used for

Skin and Soft Tissue Infections

Clindamycin powder is often used to treat skin infections, including cellulitis, abscesses, and acne. Its ability to penetrate skin tissue and its effectiveness against common skin pathogens make it ideal for treating these diseases.

Respiratory Tract Infections

Clindamycin is used to treat respiratory infections such as pneumonia, especially pneumonia caused by anaerobic bacteria. It is effective in treating both upper and lower respiratory tract infections.

Bone and Joint Infections

Due to its good bone penetration, Clindamycin is used to treat osteomyelitis and septic arthritis. Its ability to reach high concentrations in bone, makes it effective in these hard-to-treat infections.

Gynecological Infections

Clindamycin is effective against female reproductive tract infections, such as: such as pelvic inflammatory disease and bacterial vaginosis. It is often used in combination with other antibiotics to cover a broad spectrum of pathogens.

Acne Treatment

Topical clindamycin is a major ingredient in acne treatment due to its ability to reduce propionibacterium acnes and its anti-inflammatory properties. It is often used in combination with other treatments such as benzoyl peroxide to enhance efficacy.

Why Clindamycin Good for Acne

Reduces Bacterial Growth: Clindamycin targets the bacteria Propionibacterium acnes, and it plays an important role in the development of acne. By reducing the number of bacteria, it helps prevent the formation of new acne lesions.

Decreases Inflammation: Its anti-inflammatory properties help calm irritated skin, reducing the redness and swelling often associated with acne.

Good Combination with Other Treatments: Clindamycin powder can be used in combination with other acne treatments such as benzoyl peroxide and retinoids to enhance overall efficacy and provide comprehensive acne management.

Topical Clindamycin Dosage for Skin

Topical clindamycin is commonly used to treat acne and other skin infection. This dosage is very depending on your product formula and condition being treated, here are some advice from our factory, but you should test when you use clindamycin to make products

Topical clindamycin powder is available in various forms, including clindamycin gels, lotions, solutions, and foams. The concentration typically ranges from 1% to 2%.

Generally, topical clindamycin is applied once or twice daily, depending on the severity of the condition and the specific product instructions.

Clindamycin Side Effects

Clindamycin side effects is not very common, but they can occur. Such as

Gastrointestinal Issues

Nausea and Vomiting: Commonly reported by patients taking Clindamycin orally.

Diarrhea: Can range from mild to severe and may lead to dehydration.

Abdominal Pain: Stomach cramps or discomfort.

Skin Reactions

Rash: Clindamycin can cause skin rashes that may vary in severity.

Itching: Some patients experience itching or hives.

Stevens-Johnson Syndrome: A rare but serious skin reaction that requires immediate medical attention.

Liver Function Abnormalities

Elevated Liver Enzymes: Indicates potential liver stress or damage.

Jaundice: Rarely, Clindamycin can cause jaundice, marked by yellowing of the skin and eyes.

Serious Side Effects

Clostridium difficile-associated Diarrhea (CDAD)

Severe Diarrhea: Can occur during or after treatment and requires medical attention.

Pseudomembranous Colitis: Inflammation of the colon caused by overgrowth of C. difficile.

Allergic Reactions

Anaphylaxis: A severe, potentially life-threatening allergic reaction.

Angioedema: Swelling of the deeper layers of the skin, often around the eyes and lips.

Packaging and Shipping

Our clindamycin powder is carefully packed to ensure safety and preserve its properties during transportation. We use airtight, moisture-proof, and tamper-evident packaging to maintain product integrity, such as aluminum foil bag and paper drum package.

We also provide customized packaging solutions based on client requirements. Our logistics team coordinates with reliable carriers to ensure timely and secure delivery worldwide.

We always choose best way for delivery such as Fedex, DHL UPS and so on.

For 1~49Kg, we advise ship by Express, it is not big quantity, express is safe and quicker;

For 50~300 Kg, we advise ship by Air, it is quicker than sea and more competitive than Express;

More than 300 Kg, we we advise ship by Sea, it is cheaper than Air.

Where to Buy Clindamycin Online

Please contact our official website and send inquiry to Email: extract@chenlangbio.com to get newest clindamycin powder price, clindamycin COA and MSDS, or other information you need.